A troubled man survives a suicide attempt. He calls an old friend to rescue him in the middle of the night. Their journey is just beginning, and by daybreak, a tragedy will surface.

Amy has moved east from Kansas, determined to start a new life. She thinks she has found the perfect small quiet town, a great neighborhood on a quiet street. As she moves into her brand new apartment, eager to start a dream job, happy to befriend her neighbors, she finds out that not everything is as it seems, especially at the house across the street.

Paul Harris works at a small research facility on the outskirts of Boston. After a weekend tryst with a co-worker leaves him wanting more, his unreciprocated desires gradually mold into an acute infatuation. When Danielle takes interest in a new scientist at the laboratory, Paul's suppressed resentments and perverse delusions finally become unhinged, triggering a horrific course of events that mercilessly engulf a tortured past and fugitive present.